CHEMICAL COORDINATION & INTEGRATION

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Section-A

1.Match the following columns

Column-I Column-II
(A) Endocrine action (1) Hormone act on locally
(B) Autocrine action (2) Hormone act on distant target
(C) Paracrine action (3) Hormone act on same cell which produces it

A-1,B-2,C-3
A-3,B-2,C-1
A-2,B-3,C-1
A-2,B-1,C-3

2.Match the following columns

Column-I Column-II
(A) FSH (1) Synthesise the milk in breast
(B) MSH (2) Regulate the pigmentation
(C) ADH (3) Transported axonally to neurohypophysis
(D) PRL (4) Stimulate the development of ovarian follicle

A-1,B-2,C-3,D-4
A-4,B-2,C-3,D-1
A-4,B-1,C-2,D-3
A-4,B-3,C-2,D-1

3.Match the following columns

Column-I Column-II
(A) PRL (1) Gonadotropins
(B) TSH (2) Glucocorticoids
(C) ACTH (3) Thyroid hormone
(D) LH and FSH (4) Mammary glands

A-1,B-2,C-3,D-4
A-2,B-1,C-3,D-4
A-4,B-3,C-2,D-1
A-4,B-3,C-1,D-2

4.Match the following columns

Column-I Column-II
(A) Protein hormones (1) Epinephrine
(B) Steroid hormones (2) Testosterone, progesterone
(C) Iodothyronines hormones (3) Thyroid
(D) Amino acid derivatives hormones (4) Insulin and glucagon

A-1,B-2,C-3,D-4
A-4,B-3,C-2,D-1
A-4,B-2,C-3,D-1
A-4,B-2,C-1,D-3

5.A health disorder that results from the deficiency of thyroxine in adults and characterized by
I.A low metabolic rate
II.Increase in body weight
III.Tendency to retain water in tissue, is

Hypothyroidism
Simple goitre
Myxoedema
Cretinism

6.Which of the following is the function of adrenaline?

Helps in gastric juice secretion
Increase heart rate and blood pressure
Increase blood calcium
Helps in milk secretion

7.JG Cells (Juxtaglomerular cell) secretes

ANF
Erythropoietin
Rennin
Angiotensinogen

8.Which of the following is both exocrine and endocrine gland?

Liver
Pancreas
Thyroid
Adrenal

9.Gigantism and dwarfism are the disease related to

Prolactin hormone of mammary gland
Growth hormone of adenohypophysis
Leutinising hormone of the pituitary gland
Thyroid stimulating hormone of thyroid

10.Progesterone hormone is secreted by

Corpus albicans
Corpus albicans
Corpus luteum in ovaries
Corpus uteri

11.GIP (Gastric Inhibitory Peptide)

Inhibits the gastric secretion and motility
Inhibits the gastric secretion only
Activate the gastric secretion and motility
Activate the gastric secretion only

12.Lipid soluble hormone works by interacting with

Intracellular receptors
Intercellular receptors
Enzymes
Producing enzymes

13.Androgens regulates

Development of accessory sex organs
Muscular growth
Maturation of accessory sex organs
All of the above

14.Which accessory genital gland occurs only in mammalian male?

Prostate gland
Perineal gland
Cowper’s gland
Bartholin gland

15.Chemicals which are synthesized by one organism and affect the behaviour of another member of the same species, are called

Enzymes
Hormones
Flavoids
Pheromones

16.Adrenaline and noradrenaline are hormones that act as

Energy producing agents
Food storage materials
Neurotransmitters
Energy storing substances

17.Significant role of calcium balance in the body is maintained by

PTH and FSH
PTH and TCT
TCT and FSH
TCT and FSH

18.Vasopressin stimulates reabsorption of water and reduction of urine secretion. Hence, vasopressin is otherwise called

Sinovial fluid
Neurotransmitter
Antidiuretic hormone
Growth regulating substance

19.Islets of Langerhans have _A_ cells which secrete _B_ hormone. This hormone reduces the blood glucose level by converting glucose into glycogen. Islets of Langerhans have _C_ cells which secrete _D_ hormone. This hormone increase the blood glucose by converting glycogen to glucose
Choose the correct combination for A, B, C and D

A-α,B-glucagon,C-α,D-insulin
A-α,B-insulin,C-β,D-glucagon
A-β,B-insulin,C-α,D-glucagon
A-α,B-glucagon,C-β,D-insulin

20.Correct order of action of hydrophilic hormones
I. Hormones bind to plasma membrane
II. Physiological response
III. Biochemical response
IV. Generation of secondary messenger
Choose the correct option

I, II, III, IV
II, I, III, IV
I, IV, III, II
III, I, II, IV

21.I. Rapid transmission of nerve impulse
II. Slower transmission and slow acting
III. Pathway is specific
IV. Pathway is not specific
From the given statements identify the statements belongs to endocrine system and choose the correct option

I and II
III and IV
II and IV
II and III

22.Which of the following does not produce secondary messenger?

Hydrophobic hormone
Catacholamines
Proteinacious hormone
Steroid hormone

23.I. Glucagon
II. Epinephrine
III. Steroid hormone
IV. Idothyronine
Among the given hormones which needs secondary messenger

I and III
III and IV
I and II
IV and I

24.Prostaglandins are
I. fatty in nature
II. proteinaceous in nature
III. steroidal in nature
IV. glycoproteinaccous in nature
Choose the correct option

Only I
I and III
II and IV
Only IV

25.I. Pancreas
II. Testis
III. Liver
IV. Thyroid gland
V. Adrenal gland
VI. Pituitary gland
Which of the above given glands is/are not endocrine glands?

I and II
Only III
Only VI
I, II and III

26.Hormone that increases the blood calcium $Ca^{2+}$ and decrease the excretion of $Ca^{2+}$ by reabsorption is

Calcitonin
Parathormone
Insulin
ACTH

27.Adrenal medulla consists of which cells that secretes adrenaline and nor-adrenaline

Modified nerve cells
Chromaffin cells
Chief cells
Both Chromaffin and Chief cells

28.Resorption of water and electrolytes by distal tubules of kidney and thereby diuresis reducing the loss of water through urine (diuresis) is done by

Oxytocin
Vasopressin
FSH
LH

29.Which one of the following hormone is a modified amino acid?

Epinephrine
Progesterone
Prostaglandin
Oestrogen

30.Progesterone

Supports the pregnancy
Acts on the mammary gland and stimulate the formation of alveoli
Both of the above two
Controls secondary sexual characters in females

31.A child with a weak immune system. Which of the following gland could be the cause of the problem?

Thyroid gland
Parathyroid gland
Thymus
Pituitary gland

32.Which of the following is correct?

Leukaemia - Skin cancer
Diabetes - Sugar free
Rheumatic fever - Defective pacemaker
Heart attack - Radiation therapy

33.ANF has exactly opposite function of which of hormone secreted

PTH
Estrogen
Aldosterone
Androgen

34.Invertebrates possess very _A_ endocrine systems with _B_ hormones, whereas _C_ number of chemicals act as hormones and provide coordination in the vertebrates
Here A to C refers to

A-complex, B-many, C-few
A-complex, B-many, C-large
A-simple, B-few, C-large
A- complex, B-few, C-large

35.According to accepted concept of hormone action, if receptor molecules are removed from target organs, then the target organ will

Continue to respond to hormone but in opposite way
Continue to respond to the hormone without any difference
Continue to respond to hormone but will require higher concentration
Not respond to the hormone

Section-B

36.Androgens act on the _A_ and influence the male sexual behavior called _B_. These hormones produce _C_ effect on protein and carbohydrate metabolism. Choose the correct combination of A, B and C

A-PNS, B-libido, C-catabolic
A-ANS, B-libido, C-catabolic
A-CNS, B-libido, C-anabolic
A-CNS, B-libido, C-catabolic

37.Gastroinhibitory polypeptide is released/secreted by

Small intestine
Spleen
Hypothalamus
Pineal gland

38.The decline and disappearance of __ gland by the middle age is primary cause of ageing

Thyroid
Thymus
Adrenal
Parathyroid

39.Hormones are non-nutrient chemicals, which acts as __. messengers and are produced in trace amount

Intercellular
Intracellular
Extracellular
None of these

40.Toxic agents, present in food which interfere with thyroxine synthesis, lead to development of

Toxic goitre
Cretinism
Simple goiter
Thyrotoxicosis

41.I. Low metabolic rate
II. Increase in body weight
III. Tendency to retain water in tissue
Which of the following disease shows the above given symptoms?

Gigantism
Cretinism
Myxoedema
Acromegaly

42.A ten year old child, in whom anterior pituitary function is deficient, is likely to

Develop acromegaly
Be short stature but have relatively normal body proportions
Be in constant danger of becoming dehydrated
Have a high basal metabolic rate

43.Which of the following are heterocine glands
I. Thyroid
II. Parathyroid
III. Ovary
IV. Testis
V. Pituitary
VI. Pancreas
Choose the correct option

I, II and III
III, IV and VI
I, V and VI
I, IV and V

44.Which of the following is not paired correctly?

Myxoedema - Swollen facial tissues
Cretinism - Mentally retarded
Grave’s disease - Exopthalamos
Insulin - Raise blood glucose

45.Which of the following hormones does not contain a polypeptide?

Prostaglandin
Oxytocin
Insulin
Antidiuretic hormone

46.‘ANF’ is secreted by

Venous wall of heart
Atrial wall of heart
Both of these
None of these

47.In females the …A... induces the ovulation of fully mature follicle called …B... and maintain the …C… formed from remnants of the Graafian follicle after ovulation. Select the correct combination in reference to the above given statement

A-LH, B-Graafian follicles, C-pregnancy
A-FSH, B-Graafian follicles, C-corpus luteum
A-FSH, B-Graafian follicles, C-pregnancy
A-LH, B-Graafian follicles, C-corpus luteum

48.Which one of the following four glands is correctly matched with the accompanying description?

Thyroid — Hyperactivity in young children cause cretinism
Thymus — Starts undergoing atrophy after puberty
Parathyroid — Secretes parathormone, which promotes movements of Calcium ions from blood into bones during calcification
Pancreas — Delta cells of islets of Langerhans secrete a hormone, which Stimulates glycolysis in liver

49.Which one of the following endocrine glands functions as a biological clock and a neurosecretory transducer?

Adrenal gland
Thyroid gland
Pineal gland
Thymus gland

50.Which one of the following pituitary hormones does not have a target organ to act upon?

Thyrotrophin
Gonadotrophin
Adrenocorticotrophin
Somatotrophin