Email: vedanadhi@gmail.com Salem - 636115, Tamil Nadu, India
VedaNadhi

Research &
Development

Vedanadhi actively engages in research across a broad spectrum of health sciences, including:

  • Medicine and Surgery, encompassing both general practice and all super- and subspecialities.
  • Allied Health Sciences such as Nursing, Paramedical fields, Pharmacy, Physiotherapy, and Laboratory Sciences.
  • Public Health, Epidemiology, and related disciplines.

Our multidisciplinary research efforts focus on evidence synthesis, clinical outcomes, and health systems to address complex healthcare challenges. We welcome collaborations across diverse specialities and professions to advance knowledge and improve patient care.

Recent publication

"Childhood adversity and 5-HTTLPR across mental health outcomes: A transdiagnostic meta-analysis" — Vishnu Shivam

Background: Childhood maltreatment is associated with increased risk for various psychiatric disorders, although individual responses to early adversity vary. The serotonin transporter-linked polymorphic region (5-HTTLPR) has been examined as a potential moderator of sensitivity to environmental stress, but findings across studies have been inconsistent.

Objective: This meta-analysis examined whether 5-HTTLPR polymorphisms moderate the association between childhood adversity and clinically diagnosed psychiatric disorders.

Participants and settings: Fourteen studies (N = 3479) were included, representing community, population-based, and clinical samples from multiple regions.

Methods: Systematic searches of eight databases, last updated 3 December 2025, identified studies reporting 5-HTTLPR genotype, childhood adversity, and psychiatric diagnoses.

Results: Pooled analyses indicated no statistically significant interaction between childhood adversity and 5-HTTLPR genotype (ROR = 1.11, 95% CI 0.89-1.37).

Conclusion: Across available studies, evidence for an interaction between childhood adversity and 5-HTTLPR genotype was limited.

Shivam V. (2026). Childhood adversity and 5-HTTLPR across mental health outcomes: A transdiagnostic meta-analysis. Child abuse & neglect, 173, 107901.
DOI: 10.1016/j.chiabu.2026.107901

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About Vedanadhi

Vedanadhi - meaning "River of Knowledge" - is a non-sectarian initiative dedicated to the vision of "Enlightening the Future" and committed to promoting inclusive access to knowledge and research, regardless of race, ethnicity, or religion.

Mission

  1. Universal Education
  2. Universal Food Security
  3. Universal Healthcare

Disclaimer

Vedanadhi is an independently operated, non-commercial knowledge initiative founded by Vishnu Shivam. It supports research, education, scholarly publishing, and access to knowledge.

All services, resources, and engagements provided through this platform are offered free of charge, unless explicitly stated otherwise via formal, verifiable communication.

Future Changes: The scope and activities of Vedanadhi may evolve over time. Any material changes to its operating model, affiliations, or publishing activities will be communicated through the relevant website information and policies.

Research Initiatives

SREMAN — Systematic Reviews, Evidence Synthesis and Meta-Analysis Manager

SREMAN is a research software initiative designed to make systematic review and evidence synthesis workflows more accessible. It aims to support researchers, particularly those with limited funding or without access to specialised research platforms, through tools for review management, study screening, bibliography management, and related research workflows.

Explore SREMAN
Founder
VedaNadhi

Scholarly
Publishing

Vedanadhi is expanding its knowledge-sharing activities through a scholarly publishing initiative focused on systematic reviews, meta-analyses, and other forms of evidence synthesis. The programme supports the publication of research monographs and technical reports that communicate transparent methods, critical appraisal, and evidence-based findings.

Explore Scholarly Publishing Publishing Policies
VedaNadhi

Research Trainee Program

Are you a student, trainee, or early-career professional in the health sciences?

  • Join the Online Research Trainee Program, designed to empower individuals from diverse healthcare fields, including medicine, surgery and its super/sub specialities, nursing and paramedical sciences, public health, allied health, health policy, pharmacy, physiotherapy, laboratory sciences, and more.
  • This is a unique opportunity to gain hands-on experience in systematic reviews and meta-analyses, evidence synthesis, clinical research, health data interpretation, scientific writing and publications.

Recent publication

"Taste genomics and type 2 diabetes mellitus: a systematic qualitative meta-synthesis" — Vishnu Shivam, Sahana Kannan and Vishnu Harish

The current evidence suggests that genetic variations in taste receptor genes may contribute to T2DM through behavioral and metabolic mechanisms.

Shivam V, Kannan S, Harish V. (2025). Taste genomics and type 2 diabetes mellitus: a systematic qualitative meta-synthesis. Explor Endocr Metab Dis. 2025;2:101439.
DOI: 10.37349/eemd.2025.101439

Research Trainee Program
VedaNadhi

Research
Software

Introducing SREMAN

SREMAN is a software initiative associated with Vedanadhi, intended to support research-related workflows in systematic reviews and evidence synthesis.

Explore the software's purpose, available features, documentation and intended applications in the research process.

Explore SREMAN
VedaNadhi

Educational
Services

Available for all Higher secondary students.

Physics, Chemistry & Biology Question Bank Biology Video Lectures and Qbank Complete Lecture Playlist